2 edition of Studies on the morphogenesis of bacteriophage [lumbda]. found in the catalog.
Studies on the morphogenesis of bacteriophage [lumbda].
Written in English
|The Physical Object|
|Pagination||vi, 131 leaves.|
|Number of Pages||131|
Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli).It was discovered by Esther Lederberg in The wild type of this virus has a temperate life cycle that allows it to either reside within the genome of its host through lysogeny or enter into a lytic. The majority of early phage research was undertaken with coliphages (phages that infect E. coli), particularly T4 (Stahl, ; Edgar, ), evidenced by numerous studies, some of which are.
Bacteriophages are a driver of global geochemical cycles, and are a reservoir of the greatest genetic diversity on earth. The study of phages played a central role in some of the most significant discoveries in the biological sciences, from the identification of DNA as the genetic material to the deciphering of the genetic code to the development of molecular recombinant technology. A ____ bacteriophage lyse and kills the infected bacterial cells lytic (ex: T phages) Steps in the initial stages of infection of a bacterial cell by a T4 phage.
Studies on Defective Lysogenic Bacteria. I. Genetic Determination of Morphogenesis in a Temperate Bacteriophage. Foreign Title: Recherches sur les bactéries lysogènes defectives. I.-Déterminisme génétique de la morphogenèse chez un bactério-phage tempéré. Author(s): Jacob, F.; Wollman, Elie L. A novel cold-adapted siphovirus, vB_PagS_AAS21 (AAS21), was isolated in Lithuania using Pantoea agglomerans as the host for phage propagation. AAS21 has an isometric head (~85 nm in diameter) and a non-contractile flexible tail (~ × 10 nm). With a genome size of , bp, bacteriophage AAS21 is the largest Pantoea-infecting siphovirus sequenced to date.
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J. Mol. Bid. () 93, Bacteriophage Lambda Head Morphogenesis: Studies on the Role of DNA P. DAWSON, A. SKAIKA Roche Institute of Molecular Biology Nutky, N.J.U.S.A.
AND LEE D. SIMON The Institute for Cancer Research Fox Chase Center for Cancer and Medical Sciences Philadelphia, PaU.S.A. (Received 25 Julyand in revised form 25 November Cited by: Luftig RB, Wood WB, Okinaka R.
Bacteriophage T4 head morphogenesis. On the nature of gene defective heads and their role as intermediates. J Mol Biol. May 14; 57 (3)– Nossal NG.
A T4 bacteriophage mutant which lacks deoxyribonucleic acid polymerase but retains the polymerase-associated by: Kikuchi Y, King J: Genetic control of bacteriophage T4 baseplate morphogenesis. Mutants unable to form the central part of the baseplate.
J Mol Biol/S(75) PubMed CAS Article Google ScholarCited by: Bacteriophage, any of a group of viruses that infect bacteria. Bacteriophages were discovered independently by Frederick W. Twort in Great Britain () and Felix d’Herelle in France ().
Thousands of varieties of phages exist. Certain types serve key roles in laboratory research. In coliphage22 essential genes were defined by complementation studies with amber mutants. Eighteen genes were associated with phage morphogenesis: 11 with phage tail formation, and 7 with phage head formation.
The remaining four genes are discussed Cited by: VIROL () The Morphogenesis of Bacteriophage Lambda II. Identification of the Principal Structural Proteins MANUEL BUCHWALD, HELIOS MURIALDO AND LOUIS SIMINOVITCH Departments of Medical Cell Biology, Medical Sciences Building, and Medical Biophysics, The Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada Accepted.
Bacteriophage α3 procapsids were purified from E. coli slyD cells infected with α3 am(E)W4, am(J)M1, am(J)S7. The amber mutations in gene J prevent the production of the DNA-binding protein, thus arresting morphogenesis after procapsid formation. Two amber mutations were used to prevent reversion during the long incubation periods needed to.
Quantitative measurements on number, size, shape, location and time of appearance of heads and head-related structures in thin sections of induced bac. Bacteriophages are very useful models for studying the protein-derived principles of form determination in virus assembly.
Bacteriophage models cannot be ignored because of the assembly of the virus tail at the prohead portal vertex or connector, the entry point of double-stranded DNA. Bacteriophage ø29 of Bacillus subtilis, illustrated in the family portrait with bacteriophage T2 of.
The morphogenesis of phage lambda. Form-deter- mining function of the genes required for the assembly of the head. Virol PARKINSON, J. Genetics of the left arm of the chromosome of bacteriophage lambda. Genet RAY, P., and MURIALDO, H. The role of gene Nu3 in bacteriophage lambda head morphogenesis.
Journals & Books; Help Download full text in PDF Download. Share. Export. Advanced. Virology. VolumeIssue 1, JulyPages Late stages in bacteriophage λ head morphogenesis: In vitro studies on the action of the bacteriophage λ D-gene and W-gene products.
Georgopoulos CP, Hendrix RW, Kaiser AD, Wood WB. Role of the host cell in bacteriophage morphogenesis: effects of a bacterial mutation on T4 head assembly. Nat New Biol. Sep 13; (89)– Georgopoulos CP, Hohn B. Identification of a host protein necessary for bacteriophage morphogenesis (the groE gene product).
Dear Colleagues, Bacteriophages, the viruses infecting bacterial cells, were first described years ago, inby Frederick Twort. The scientist who introduced the name “bacteriophage” was Felix d’Herelle, who investigated these viruses for many years, leading to new fields of research, including bacteriophage therapy.
The structure of bacteriophage lambda has been studied extensively by several groups using a variety of physical and chemical techniques. However, many aspects of bacteriophage structure remain unreasolved.
It is not known how the DNA is arranged three-dimensionally within the capsid, nor is the mechanism of packaging understood. Dawson P, Skalka A. Bacteriophage lambda head morphogenesis: studies on the role of DNA. J Mol Biol. Apr 5; 93 (2)– Lickfeld KG, Menge B. Morphogenesis of bacteriophage lambda: electron microscopy of thin sections.
J Mol Biol. May 15; (2)– Lactobacillus rhamnosus Pen is a human endogenous strain used for the production of probiotic formula, which is effective in the prevention of antibiotic-associated diarrhoea. Our study showed that this probiotic strain releases bacteriophage BH1 without the addition of any inducing agent.
Our research revealed that phage BH1 has a circular genome with a length of nt and a GC content of. Fujisawa, H., and Hayashi, M.,Assembly of bacteriophage øX Identification of a virion capsid precursor and proposal of a model for the functions of bacteriophage gene products during morphogenesis, J.
Virol. Bacteriophage are viruses of bacteria and arguably are the most numerous "organisms" on history of phage study is captured, in part, in the books published on the topic. This is a list of over monographs on or related to phages. INTRODUCTION •Filamentous rod shaped bacteriophage •Belongs to family Inoviridae •A small phage •Has circular single stranded DNA of nucleotides in length •During replication inside the host cell M13 is present in double stranded replicative form (RF) •During morphogenesis the DNA is converted into single stranded.
Biochemistry All Publications/Website. OR SEARCH CITATIONS. Abstract. Mature particles of bacteriophage lambda are composed of about equal amounts of protein and DNA. Each phage contains one double-stranded DNA molecule encapsulated in an icosahedral head, which is about 50 nm ( μ) in diameter; a flexible tubular tail, which is about nm ( μ) long and terminates in a fiber, projects from the head (Kellenberger and Edgar, ).Wunderli H, van den Brock J, Kellenberger E.
Studies related to the head-maturation pathway of bacteriophage T4 and T2. I. Morphology and kinetics of intracellular particles produced by mutants in the maturation genes.
J Supramol Struct ; – PubMed CrossRef Google Scholar.Molecular Biology of Bacteriophage T4 highlights the value of this biological system as a research and teaching tool. The book is a sequel to the edition and is organized into six major sections: DNA metabolism, regulation of gene expression, phage morphogenesis, structure and function of selected proteins, host-phage interactions, and experiments in T4 molecular genetics.